Endocrine Abstracts

Introduction: Carney complex is a rare autosomal dominant genetic disorder which develops secondary to mutation in the PRKAR1A gene located in the 17q22-24 region. It is commonly characterised by the association between spotty skin pigmentation, cardiac myxoma and secretory endocrine tumors.Case presentation: A 15.8-year-old boy known with PRKAR1A mutation diagnosed based on his personal history – cutaneous papiloma of the neck resected at the age o...

BackgroundProlactinomas are the most frequent type of hormone-secreting pituitary adenomas. Prolactin(PRL)-receptor mediates intracellular signaling pathways that contribute to weight gain, dyslipidemia, impaired fasting glucose (IFG), type 2 diabetes mellitus (T2DM) and cardiovascular disease, parameters that improve along with PRL level control on dopamine agonist (DA) therapy.AimTo assess metabolic disturb...